Wednesday, September 9, 2015

Tumor markers, PET scans and other measures

It's hard not to get caught up in the numbers, especially the dreaded CA 27-29 tumor marker. Mine went through the roof this time, up almost 100 points, the highest it's ever been. My first response was panic, fear, and an overwhelming sense of dread.

Thankfully it didn't last very long. Pretty soon I came to my senses and decided the number didn't mean the cancer was worse. I was certain that it was in fact, better. I felt better, much better. If the cancer was anywhere close to where it had been when I started this journey or worse, there was no way I could feel this good, both physically and mentally. I blew it off and went on about my week.

The day after the blood tests, I had a PET scan, so I decided not to fret unless the PET scan results suggested I should. Today I got those results, and low and behold, they were good. As is typical of my life, the results were......mixed, weird, a bit perplexing, especially when considering the elevated tumor markers. The PET summary read....Mixed response of mild progression and predominantly mild regression.  My oncologist was concerned about the tumor marker number, but happy with the PET and said "stay the course" believing I was still taking the Ibrance and Femara cocktail.

The nurse practitioner, who I see more than the oncologist, asked me to reconsider going back on  Ibrance and I told her I would think about it. It's tough to know what to do at this point. I feel strongly that my alternative approach is working, but I also believe in hitting it with whatever we have. That said, I can't get my head around the side effects, and particularly the weakening of the immune system.

Breast cancer tumor marker image from MIT Spectrum.

Explaining why the CA 27-29 number was elevated

After doing more research, my best guess for why the number went up was because of dying cancer cells. At least that's what I choose to believe.  I found this in a description of the tumor markers.

Levels usually drop following effective treatment, although they may spike in the first few weeks after treatment is started, a result of dying cancer cells spilling their contents into the bloodstream.

That's my story and I'm sticking to it!

3 comments:

  1. I'm on Ibrance, my markers have gone from 187 at the end of August to 1250 as of tuesday. But i am not worrying about it because I feel wonderful and I just think something else is making them rise :)

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